September 2014

Mayeta Clark 2015

Immunological markers of vivax exposure and immunity: A Systematic Review and Meta-analysis

September 9, 2014

This study standardised protective immune responses across multiple populations to identify biomarkers of protective vivax immunity across populations of varying malaria transmission.

Read More

Global extent of chloroquine-resistant Plasmodium vivax a systematic review and meta-analysis

September 8, 2014

A meta-analysis of >191 clinical trials highlighting the complexity of defining P. vivax antimalarial efficacy. The paper demonstrates that the extent of chloroquine resistant P. vivax is far greater than previously appreciated

Read More

Making the most of clinical data: reviewing the role of pharmacokinetic-pharmacodynamic models of anti-malarial drugs

September 1, 2014

Our invited review highlighted that current pharmacokinetic-pharmacodynamic models exclude important factors such as host immunity and complexities of drug action. We highlighted a lack of statistical rigour in parameter estimation.

Read More