September 9, 2014
This study standardised protective immune responses across multiple populations to identify biomarkers of protective vivax immunity across populations of varying malaria transmission.
September 8, 2014
A meta-analysis of >191 clinical trials highlighting the complexity of defining P. vivax antimalarial efficacy. The paper demonstrates that the extent of chloroquine resistant P. vivax is far greater than previously appreciated
Making the most of clinical data: reviewing the role of pharmacokinetic-pharmacodynamic models of anti-malarial drugs
September 1, 2014
Our invited review highlighted that current pharmacokinetic-pharmacodynamic models exclude important factors such as host immunity and complexities of drug action. We highlighted a lack of statistical rigour in parameter estimation.