February 2022

Mayeta Clark 2015

A fluorometric assay to determine the protective effect of glucose-6-phosphate dehydrogenase (G6PD) against a Plasmodium spp. infection in females heterozygous for the G6PD gene: proof of concept in Plasmodium falciparum

February 22, 2022

Objective: Glucose-6-phosphate dehydrogenase (G6PD) deficiency offers some protection against malaria; however, the degree of protection is poorly described and likely…

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Scoping Review of Antimalarial Drug Candidates in Phase I and II Drug Development

February 15, 2022

The emergence and spread of parasite resistance to currently available antimalarials has highlighted the importance of developing novel antimalarials. This…

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Global diversity and balancing selection of 23 leading Plasmodium falciparum candidate vaccine antigens

February 2, 2022

Investigation of the diversity of malaria parasite antigens can help prioritize and validate them as vaccine candidates and identify the…

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Tafenoquine for children: a step towards implementation

February 1, 2022

After several decades of development, tafenoquine, an 8-aminoquinoline compound, was registered by the US Food and Drug Administration on July…

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Spatial codistribution of HIV, tuberculosis and malaria in Ethiopia

February 1, 2022

Background: HIV, tuberculosis (TB) and malaria are the three most important infectious diseases in Ethiopia, and sub-Saharan Africa. Understanding the…

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