Reducing malaria transmission in forest-going mobile and migrant populations in Lao PDR and Cambodia: protocol for stepped-wedge cluster-randomised controlled trial
September 24, 2022
Countries of the Greater Mekong Sub-region aim to achieve malaria elimination by 2030. In the region, malaria is concentrated in…
Relationship of circulating Plasmodium falciparum lifecycle stage to circulating parasitemia and total parasite biomass
September 23, 2022
We previously showed in Papua that circulating Plasmodium falciparum causing severe malaria are younger than those causing uncomplicated malaria1. Thomson-Luque et al.2 subsequently…
Safety of single-dose primaquine as a Plasmodium falciparum gametocytocide: a systematic review and meta-analysis of individual patient data
September 16, 2022
Background: In 2012, the World Health Organization (WHO) recommended single low-dose (SLD, 0.25 mg/kg) primaquine to be added as a…
Genetic Variants of Glucose-6-Phosphate Dehydrogenase and Their Associated Enzyme Activity: A Systematic Review and Meta-Analysis
September 14, 2022
Low glucose-6-phosphate dehydrogenase enzyme (G6PD) activity is a key determinant of drug-induced haemolysis. More than 230 clinically relevant genetic variants…
Increased circulating myeloid-derived suppressor cells in vivax malaria and severe falciparum malaria
September 6, 2022
Background: Circulating myeloid-derived-suppressor-cells (MDSC) with immunosuppressive function are increased in human experimental Plasmodium falciparum infection, but have not been studied…