November 2022

Mayeta Clark 2015

Targeting malaria parasites with novel derivatives of azithromycin

November 30, 2022

Introduction:¬†The spread of artemisinin resistant¬†Plasmodium falciparum¬†parasites is of global concern and highlights the need to identify new antimalarials for future…

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Quantification of Tafenoquine and 5,6-Orthoquinone Tafenoquine by UHPLC-MS/MS in Blood, Plasma, and Urine, and Application to a Pharmacokinetic Study

November 24, 2022

Analytical methods for the quantification of the new 8-aminoquinoline antimalarial tafenoquine (TQ) in human blood, plasma and urine, and the…

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Pathogenicity and virulence of malaria: sticky problems and tricky solutions

November 23, 2022

Infections with Plasmodium falciparum and Plasmodium vivax cause over 600,000 deaths each year, concentrated in Africa and in young children,…

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Longitudinal IgG antibody responses to Plasmodium vivax blood-stage antigens during and after acute vivax malaria in individuals living in the Brazilian Amazon

November 23, 2022

Background: To make progress towards malaria elimination, a highly effective vaccine targeting Plasmodium vivax is urgently needed. Evaluating the kinetics…

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The RTS,S malaria vaccine: Current impact and foundation for the future

November 16, 2022

The RTS,S vaccine has recently been recommended for implementation as a childhood vaccine in regions with moderate-to-high malaria transmission. We…

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Eotaxin-2 and eotaxin-3 in malaria exposure and pregnancy

November 15, 2022

Background: Eotaxin-1 concentrations in plasma have been inversely associated with malaria exposure, malaria infection and pregnancy, but the effect of…

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Effect of out-of-village working activities on recent malaria exposure in the Peruvian Amazon using parametric g-formula

November 9, 2022

In the Amazon Region of Peru, occupational activities are important drivers of human mobility and may increase the individual risk…

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