Related Projects
- Development of Novel Antimalarial Drugs that Target Proteostasis
- Epidemiological modelling for malaria elimination
- Evaluation and prediction of the effect of combinations of antimalarial drugs
- Identifying better treatments for uncomplicated malaria
- Impact of declining transmission on malaria treatment outcomes, immunity and risk of rebound
- Malaria vaccine development and evaluation
- Rapid point-of contact test for malaria surveillance based on serology
- Understanding kinetics of antigens used in rapid diagnostic tests for malaria
- Within-host malaria modelling to improve the treatment of malaria
Related Publications
- A dynamic stress model explains the delayed drug effect in artemisinin treatment of Plasmodium falciparum
- A mechanistic model quantifies artemisinin-induced parasite growth retardation in blood-stage Plasmodium falciparum infection
- Altered temporal response of malaria parasites determines differential sensitivity to artemisinin
- An artesunate pharmacometric model to explain therapeutic responses in falciparum malaria
- Anti-Gametocyte Antigen Humoral Immunity and Gametocytemia During Treatment of Uncomplicated Falciparum Malaria: A Multi-National Study
- Antibody targets on the surface of Plasmodium falciparum-infected erythrocytes that are associated with immunity to severe malaria in young children
- Antibody to Plasmodium falciparum variant surface antigens, var gene transcription and ABO blood group in children with severe or uncomplicated malaria
- Characterizing antibody responses to mosquito salivary antigens of the Southeast Asian vectors of malaria and dengue with a human challenge model of controlled exposure: a protocol
- Community-based molecular and serological surveillance of subclinical malaria in Myanmar
- Comparison of Antibody Responses and Parasite Clearance in Artemisinin Therapeutic Efficacy Studies in the Democratic Republic of Congo and Asia
- Contribution of Functional Antimalarial Immunity to Measures of Parasite Clearance in Therapeutic Efficacy Studies of Artemisinin Derivatives
- Cost-Effectiveness Analysis of Sex-Stratified Plasmodium vivax Treatment Strategies Using Available G6PD Diagnostics to Accelerate Access to Radical Cure
- Dealing with indeterminate outcomes in antimalarial drug efficacy trials: a comparison between complete case analysis, multiple imputation and inverse probability weighting
- Declining transmission and immunity to malaria and emerging artemisinin resistance in Thailand: a longitudinal study
- Developing a multivariate prediction model of antibody features associated with protection of malaria-infected pregnant women from placental malaria
- Early and late mortality after malaria in young children in Papua, Indonesia
- Evaluating antimalarial efficacy in single-armed and comparative drug trials using competing risk survival analysis: a simulation study
- Evaluation of the effectiveness of topical repellent distributed by village health volunteer networks against Plasmodium spp. infection in Myanmar: A stepped-wedge cluster randomised trial
- Global economic costs due to vivax malaria and the potential impact of its radical cure: A modelling study
- Host immunity to Plasmodium falciparum and the assessment of emerging artemisinin resistance in a multinational cohort
- Identifying and combating the impacts of COVID-19 on malaria
- Immunological markers of vivax exposure and immunity: A Systematic Review and Meta-analysis
- Implications of population-level immunity for the emergence of artemisinin-resistant malaria: a mathematical model.
- In silico investigation of the decline in clinical efficacy of artemisinin combination therapies due to increasing artemisinin and partner drug resistance
- Intermittent screening and treatment for malaria complementary to routine immunisation in the first year of life in Papua, Indonesia: a cluster randomised superiority trial
- Investigating causal pathways in severe falciparum malaria: A pooled retrospective analysis of clinical studies
- Investigating the efficacy of triple artemisinin-based combination therapies (TACTs) for treating Plasmodium falciparum malaria patients using mathematical modelling
- Iron deficiency during pregnancy is associated with a reduced risk of adverse birth outcomes in a malaria-endemic area in a longitudinal cohort study
- Longitudinal trends in malaria testing rates in the face of elimination in eastern Myanmar: a 7-year observational study
- Major burden of severe anemia from non-falciparum malaria species in southern Papua: A hospital-based surveillance study
- Making the most of clinical data: reviewing the role of pharmacokinetic-pharmacodynamic models of anti-malarial drugs
- Malaria morbidity and mortality following introduction of a universal policy of artemisinin-based treatment for malaria in Papua, Indonesia: A longitudinal surveillance study
- Mechanistic Modeling of Primaquine Pharmacokinetics, Gametocytocidal Activity, and Mosquito Infectivity
- Modeling the dynamics of Plasmodium falciparum gametocytes in humans during malaria infection
- Population Pharmacokinetics and Pharmacodynamics of Chloroquine in a Plasmodium Vivax Volunteer Infection Study
- Pregnancy-specific malarial immunity and risk of malaria in pregnancy and adverse birth outcomes: a systematic review
- Quantification of parasite clearance in Plasmodium knowlesi infections
- Quantification of the dynamics of antibody response to malaria to inform sero-surveillance in pregnant women
- Quantifying the association between malaria in pregnancy and stillbirth: A systematic review and meta-analysis
- Reducing the risk of Plasmodium vivax after falciparum infections in co-endemic areas – a radomised controlled trial
- Risk of Plasmodium vivax parasitaemia after Plasmodium falciparum infection: a systematic review and meta-analysis.
- Safety of primaquine in infants with Plasmodium vivax malaria in Papua, Indonesia.
- Scoping Review of Antimalarial Drug Candidates in Phase I and II Drug Development
- Seeking an optimal dosing regimen for OZ439/DSM265 combination therapy for treating uncomplicated falciparum malaria
- Severe malaria, Pascalian therapeutics and the US FDA
- Short-course primaquine for the radical cure of Plasmodium vivax malaria: a multicentre, randomised, placebo-controlled non-inferiority trial
- Supervised versus unsupervised primaquine radical cure for the treatment of falciparum and vivax malaria in Papua, Indonesia: a cluster-randomised, controlled, open-label superiority trial
- Surveillance to achieve malaria elimination in eastern Myanmar: a 7-year observational study
- Targeting the cell stress response of Plasmodium falciparum to overcome artemisinin resistance
- The clinical pharmacology of tafenoquine in the radical cure of Plasmodium vivax malaria: An individual patient data meta-analysis
- The clinical pharmacology of tafenoquine in the radical cure of Plasmodium vivax malaria: An individual patient data meta-analysis
- The effect of chloroquine dose and primaquine on Plasmodium vivax recurrence: a WorldWide Antimalarial Resistance Network systematic review and individual patient pooled meta-analysis
- The efficacy of dihydroartemisininpiperaquine and artemether-lumefantrine with and without primaquine on Plasmodium vivax recurrence: A systematic review and individual patient data meta-analysis
- The haematological consequences of Plasmodium vivax malaria after chloroquine treatment with and without primaquine: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-analysis
- The heterogeneity of symptom reporting across study sites: a secondary analysis of a randomised placebo-controlled multicentre antimalarial trial
- The impact of targeted malaria elimination with mass drug administrations on falciparum malaria in Southeast Asia: A cluster randomised trial.
- The relationship between anti-merozoite antibodies and incidence of P. falciparum malaria: A systematic review and meta-analysis.
- The risk of morbidity and mortality following recurrent malaria in Papua, Indonesia: a retrospective cohort study
- The risk of Plasmodium vivax parasitaemia after P. falciparum malaria: An individual patient data meta-analysis from the WorldWide Antimalarial Resistance Network
- Unsupervised primaquine for the treatment of Plasmodium vivax malaria relapses in southern Papua: a hospital-based cohort study
- Variation in Glucose-6-Phosphate Dehydrogenase activity following acute malaria
- Within-host modeling of blood-stage malaria