Lee completed a BSc(Hons) at the University of Melbourne, majoring in Botany. He then completed a PhD in the laboratories of Associate Professor Stuart Ralph and Professor Geoff McFadden, followed by a postdoctoral position with Dr Michael Duffy, both at the University of Melbourne.
His research has combined equal parts bioinformatics and wet-lab work, including transcriptomics, whole-genome sequencing, molecular and cell biology, and CRISPR-Cas9. His projects have investigated the role and mechanism of alternative splicing in apicomplexans, and the function of histone modifications and epigenetic regulation of transcription in the malaria parasite.
He joined Professor James Beeson’s lab in 2021 to research the immune response to Plasmodium vivax malaria.