Tharkeshi Dharmaratne


Tharkeshi is a PhD student at the Melbourne School of Population and Global Health investigating statistical methods to quantify and calibrate the dynamic antibody responses to malaria and is supervised by Prof Julie A. Simpson, A/Prof Freya Fowkes (Burnet Institute), Dr. Sophie Zaloumis, Dr. Saber Dini and Dr. David Price. She mainly seeks to develop statistical approaches to characterise the highly dynamic profiles of the antibody responses, and in turn, identify the key features that best classifies these antibody trajectories. For this purpose, longitudinal antibody data from two studies will be analysed: (i) pregnant women from the Thai-Myanmar border and (ii) participants from four countries in South East Asia enrolled in a cluster randomized controlled trial of mass drug administration. Optimal sampling times for quantifying the decline in antibody levels, will also be determined for future studies assessing population level interventions.