Developing better tools for diagnosing patients and populations at risk of primaquine induced haemolysis
Primaquine is the only widely available antimalarial agent with activity against the late gametocyte stages of P. falciparum and the…
Identifying populations at risk of multidrug resistant malaria
One of the greatest threats to malaria elimination is the emergence and spread of multidrug resistant malaria. In the Greater…
Identifying better treatments for uncomplicated malaria
Early diagnosis and highly effective treatment is a key strategy to control and eliminate the parasite. An inevitable consequence of…
Operational research on access and coverage of malaria interventions
Maximizing the coverage of malaria control interventions and prompt diagnosis and treatment of malaria are crucial for achieving malaria elimination….
Malaria vaccine development and evaluation
Ongoing research by ACREME members aims to identify key targets and mechanisms of immunity to malaria to discover and prioritise…
Rapid point-of contact test for malaria surveillance based on serology
As malaria transmission declines, conventional surveillance for malaria based on case reporting data, malaria RDT testing, and cross-sectional parasitaemia surveys…
Relatedness of successive Plasmodium vivax infections
To-date we have a limited understanding of the biology the dormant P. vivax liver stages (i.e. the hypnozoites) and the…
Using pharmacogenomics to improve anti-malarial treatment
Despite increased malaria control measures and falling malaria cases, Plasmodium vivax persists. The reasons for the greater persistence of P….
Developing serological markers of recent exposure to malaria
One key challenge for malaria elimination is the development of better surveillance tools. As the number of cases of malaria…
Understanding kinetics of antigens used in rapid diagnostic tests for malaria
Rapid diagnostic tests (RDTs) provide point-of-care tests for diagnosing malaria in communities. A range of RDTs has been developed to…