Evidence uptake is only part of the process: Stakeholders’ insights on WHO treatment guideline recommendation processes for radical cure of P. vivax malaria
March 14, 2024
Health policy processes should be evidence-informed, transparent and timely, but these processes are often unclear to stakeholders outside the immediate…
Comparing malaria risk exposure in rural Cambodia population using GPS tracking and questionnaires
March 12, 2024
The Great Mekong Subregion has attained a major decline in malaria cases and fatalities over the last years, but residual…
Progress towards safer and more effective radical cure of Plasmodium vivax
March 4, 2024
Plasmodium vivax causes a substantial burden of disease in the Americas, the Horn of Africa, and Asia-Pacific. The parasite forms dormant…
Using serological diagnostics to characterize remaining high-incidence pockets of malaria in forest-fringe Cambodia
February 15, 2024
Background Over the last decades, the number of malaria cases has drastically reduced in Cambodia. As the overall prevalence of…
Tafenoquine following G6PD screening versus primaquine for the treatment of vivax malaria in Brazil: A cost-effectiveness analysis using a transmission model
January 9, 2024
Background Malaria transmission modelling has demonstrated the potential impact of semiquantitative glucose-6-phosphate dehydrogenase (G6PD) testing and treatment with single-dose tafenoquine…
A cross-sectional study to ascertain malaria prevalence among asymptomatic travellers arriving on the Lihir Group of Islands, Papua New Guinea: implications for elimination efforts
November 29, 2023
Background The Lihir Islands of Papua New Guinea host a mining operation that has resulted in a mine-impacted zone (MIZ)…
Comparison of new computational method for spatial modelling of malaria
November 21, 2023
Geostatistical analysis of health data is increasingly used to model spatial variation in malaria prevalence, burden, and other metrics. Traditional…
Primaquine radical cure in patients with Plasmodium falciparum malaria in areas co-endemic for P falciparum and Plasmodium vivax (PRIMA): a multicentre, open-label, superiority randomised controlled trial
November 15, 2023
Background In areas co-endemic for Plasmodium vivax and Plasmodium falciparum there is an increased risk of P vivax parasitaemia following P falciparum malaria. Radical cure is currently only…
Effect of adherence to primaquine on the risk of Plasmodium vivax recurrence: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-analysis
October 10, 2023
Background Imperfect adherence is a major barrier to effective primaquine radical cure of Plasmodium vivax. This study investigated the effect of…
Effect of primaquine dose on the risk of recurrence in patients with uncomplicated Plasmodium vivax: a systematic review and individual patient data meta-analysis
September 22, 2023
Primaquine is used to eliminate Plasmodium vivax hypnozoites, but its optimal dosing regimen remains unclear. We undertook a systematic review and individual…