Publications

Mayeta Clark 2015

Supervised versus unsupervised primaquine radical cure for the treatment of falciparum and vivax malaria in Papua, Indonesia: a cluster-randomised, controlled, open-label superiority trial

March 22, 2022

Background: There is a high risk of Plasmodium vivax recurrence in patients treated for Plasmodium falciparum malaria in co-endemic areas. Primaquine…

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Haematological consequences of acute uncomplicated falciparum malaria: a WorldWide Antimalarial Resistance Network pooled analysis of individual patient data

March 7, 2022

Background: Plasmodium falciparum malaria is associated with anaemia-related morbidity, attributable to host, parasite and drug factors. We quantified the haematological response…

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Quantification of the dynamics of antibody response to malaria to inform sero-surveillance in pregnant women

March 5, 2022

Background: Malaria remains a major public health threat and tools sensitive to detect infections in low malaria transmission areas are needed…

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Mechanistic Modeling of Primaquine Pharmacokinetics, Gametocytocidal Activity, and Mosquito Infectivity

March 1, 2022

Clinical studies have shown that adding a single 0.25 mg base/kg dose of primaquine to standard antimalarial regimens rapidly sterilizes…

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Scoping Review of Antimalarial Drug Candidates in Phase I and II Drug Development

February 15, 2022

The emergence and spread of parasite resistance to currently available antimalarials has highlighted the importance of developing novel antimalarials. This…

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Supervised versus unsupervised primaquine radical cure for the treatment of falciparum and vivax malaria in Papua, Indonesia: a cluster-randomised, controlled, open-label superiority trial

October 25, 2021

Background: There is a high risk of Plasmodium vivax recurrence in patients treated for Plasmodium falciparum malaria in co-endemic areas. Primaquine…

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Longitudinal trends in malaria testing rates in the face of elimination in eastern Myanmar: a 7-year observational study

September 22, 2021

Background: Providing at-risk communities with uninterrupted access to early diagnosis and treatment is a key component in reducing malaria transmission and…

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Surveillance of molecular markers of Plasmodium falciparum artemisinin resistance (kelch13 mutations) in Papua New Guinea between 2016 and 2018

July 10, 2021

Plasmodium falciparum resistance to artemisinin-based combination therapy (ACT) is a global threat to malaria control and elimination efforts. Mutations in the P. falciparum kelch13 gene…

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