Optimizing Myanmar’s community-delivered malaria volunteer model: a qualitative study of stakeholders’ perspectives
February 8, 2021
Background In parallel with the change of malaria policy from control to elimination and declines in the malaria burden in…
The risk of Plasmodium vivax parasitaemia after P. falciparum malaria: An individual patient data meta-analysis from the WorldWide Antimalarial Resistance Network
November 19, 2020
Background There is a high risk of Plasmodium vivax parasitaemia following treatment of falciparum malaria. Our study aimed to quantify this risk…
Monitoring Plasmodium falciparum and Plasmodium vivax using microsatellite markers indicates limited changes in population structure after substantial transmission decline in Papua New Guinea
September 28, 2020
Monitoring the genetic structure of pathogen populations may be an economical and sensitive approach to quantify the impact of control…
Evaluation of the effectiveness of topical repellent distributed by village health volunteer networks against Plasmodium spp. infection in Myanmar: A stepped-wedge cluster randomised trial
August 20, 2020
Background The World Health Organization has yet to endorse deployment of topical repellents for malaria prevention as part of public…
Identifying and combating the impacts of COVID-19 on malaria
July 30, 2020
Background The COVID-19 pandemic has resulted in millions of infections, hundreds of thousands of deaths and major societal disruption due…
Innate immune responses to malaria-infected erythrocytes in pregnant women: Effects of gravidity, malaria infection, and geographic location
July 29, 2020
Background Malaria in pregnancy causes maternal, fetal and neonatal morbidity and mortality, and maternal innate immune responses are implicated in…
Implementing parasite genotyping into national surveillance frameworks: feedback from control programmes and researchers in the Asia–Pacific region
July 27, 2020
The Asia–Pacific region faces formidable challenges in achieving malaria elimination by the proposed target in 2030. Molecular surveillance of Plasmodium parasites can…
Plasma cell-free DNA predicts pediatric cerebral malaria severity
June 18, 2020
Background Prediction of adverse outcomes in cerebral malaria (CM) is difficult. We hypothesized that cell-free DNA (cfDNA) levels would facilitate…
Transcriptional profiling and immunophenotyping show sustained activation of blood monocytes in subpatent Plasmodium falciparum infection
June 18, 2020
Objectives Malaria, caused by Plasmodium infection, remains a major global health problem. Monocytes are integral to the immune response, yet their transcriptional…
Population Pharmacokinetics and Pharmacodynamics of Chloroquine in a Plasmodium Vivax Volunteer Infection Study
May 16, 2020
Chloroquine has been used for the treatment of malaria for more than 70 years; however, chloroquine pharmacokinetic (PK) and pharmacodynamic…