Related Projects
- Access and adherence to malaria interventions
- Developing better tools for diagnosing patients and populations at risk of primaquine induced haemolysis
- Development of Novel Antimalarial Drugs that Target Proteostasis
- Epidemiological modelling for malaria elimination
- Evaluation and prediction of the effect of combinations of antimalarial drugs
- Identifying better treatments for uncomplicated malaria
- Identifying populations at risk of multidrug resistant malaria
- Malaria vaccine development and evaluation
- Operational research on access and coverage of malaria interventions
- Using pharmacogenomics to improve anti-malarial treatment
- Within-host malaria modelling to improve the treatment of malaria
Related Publications
- Scoping Review of Antimalarial Drug Candidates in Phase I and II Drug Development
- Mechanistic Modeling of Primaquine Pharmacokinetics, Gametocytocidal Activity, and Mosquito Infectivity
- Supervised versus unsupervised primaquine radical cure for the treatment of falciparum and vivax malaria in Papua, Indonesia: a cluster-randomised, controlled, open-label superiority trial
- Surveillance of molecular markers of Plasmodium falciparum artemisinin resistance (kelch13 mutations) in Papua New Guinea between 2016 and 2018
- Global economic costs due to vivax malaria and the potential impact of its radical cure: A modelling study
- Developing a multivariate prediction model of antibody features associated with protection of malaria-infected pregnant women from placental malaria
- Seeking an optimal dosing regimen for OZ439/DSM265 combination therapy for treating uncomplicated falciparum malaria
- Glucose-6-phosphate dehydrogenase activity in individuals with and without malaria: Analysis of clinical trial, cross-sectional and case-control data from Bangladesh
- Optimizing Myanmar’s community-delivered malaria volunteer model: a qualitative study of stakeholders’ perspectives
- The risk of Plasmodium vivax parasitaemia after P. falciparum malaria: An individual patient data meta-analysis from the WorldWide Antimalarial Resistance Network
- Plasma cell-free DNA predicts pediatric cerebral malaria severity
- Innate immune responses to malaria-infected erythrocytes in pregnant women: Effects of gravidity, malaria infection, and geographic location
- Evaluation of the effectiveness of topical repellent distributed by village health volunteer networks against Plasmodium spp. infection in Myanmar: A stepped-wedge cluster randomised trial
- Identifying and combating the impacts of COVID-19 on malaria
- Cost-Effectiveness Analysis of Sex-Stratified Plasmodium vivax Treatment Strategies Using Available G6PD Diagnostics to Accelerate Access to Radical Cure
- Population Pharmacokinetics and Pharmacodynamics of Chloroquine in a Plasmodium Vivax Volunteer Infection Study
- Multifunctional Antibodies Are Induced by the RTS,S Malaria Vaccine and Associated With Protection in a Phase 1/2a Trial
- The risk of morbidity and mortality following recurrent malaria in Papua, Indonesia: a retrospective cohort study
- Tafenoquine for the radical cure and prevention of malaria: the importance of testing for G6PD deficiency
- Pregnancy-specific malarial immunity and risk of malaria in pregnancy and adverse birth outcomes: a systematic review
- Malaria-related hospitalization during childhood in Papua, Indonesia: A retrospective cohort study
- Dealing with indeterminate outcomes in antimalarial drug efficacy trials: a comparison between complete case analysis, multiple imputation and inverse probability weighting
- Progress towards vaccines to protect pregnant women from malaria
- Microscopic and submicroscopic Plasmodium falciparum infection, maternal anaemia and adverse pregnancy outcomes in Papua New Guinea: a cohort study
- Contribution of Functional Antimalarial Immunity to Measures of Parasite Clearance in Therapeutic Efficacy Studies of Artemisinin Derivatives
- Protective Immunity against Severe Malaria in Children Is Associated with a Limited Repertoire of Antibodies to Conserved PfEMP1 Variants
- Early and late mortality after malaria in young children in Papua, Indonesia
- Modeling the dynamics of Plasmodium falciparum gametocytes in humans during malaria infection
- The efficacy of dihydroartemisininpiperaquine and artemether-lumefantrine with and without primaquine on Plasmodium vivax recurrence: A systematic review and individual patient data meta-analysis
- Investigating causal pathways in severe falciparum malaria: A pooled retrospective analysis of clinical studies
- The haematological consequences of Plasmodium vivax malaria after chloroquine treatment with and without primaquine: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-analysis
- Short-course primaquine for the radical cure of Plasmodium vivax malaria: a multicentre, randomised, placebo-controlled non-inferiority trial
- Malaria morbidity and mortality following introduction of a universal policy of artemisinin-based treatment for malaria in Papua, Indonesia: A longitudinal surveillance study
- Evaluating antimalarial efficacy in single-armed and comparative drug trials using competing risk survival analysis: a simulation study
- Safety of primaquine in infants with Plasmodium vivax malaria in Papua, Indonesia.
- Induction and decay of functional complement-fixing antibodies by the RTS,S malaria vaccine in children, and a negative impact of malaria exposure
- The impact of targeted malaria elimination with mass drug administrations on falciparum malaria in Southeast Asia: A cluster randomised trial.
- Targets of complement-fixing antibodies in protective immunity against malaria in children
- Risk of Plasmodium vivax parasitaemia after Plasmodium falciparum infection: a systematic review and meta-analysis.
- In silico investigation of the decline in clinical efficacy of artemisinin combination therapies due to increasing artemisinin and partner drug resistance
- Artemisinin kills malaria parasites by damaging proteins and inhibiting the proteasome
- Implications of population-level immunity for the emergence of artemisinin-resistant malaria: a mathematical model.
- Within-host modeling of blood-stage malaria
- Investigating the efficacy of triple artemisinin-based combination therapies (TACTs) for treating Plasmodium falciparum malaria patients using mathematical modelling
- The effect of chloroquine dose and primaquine on Plasmodium vivax recurrence: a WorldWide Antimalarial Resistance Network systematic review and individual patient pooled meta-analysis
- Unsupervised primaquine for the treatment of Plasmodium vivax malaria relapses in southern Papua: a hospital-based cohort study
- Comparison of artemether-lumefantrine and chloroquine with and without primaquine for the treatment of Plasmodium vivax in Ethiopia: a randomized controlled trial
- Sulphadoxine-pyrimethamine plus azithromycin for the prevention of low birthweight in Papua New Guinea: a randomised controlled trial
- The effect of dose on the antimalarial efficacy of artemether-lumefantrine: a pooled analysis of individual patient data
- Altered temporal response of malaria parasites determines differential sensitivity to artemisinin
- Dihydroartemisinin-piperaquine treatment of multidrug resistant falciparum and vivax malaria in pregnancy
- Intermittent preventive treatment for malaria in Papua New Guinean infants exposed to Plasmodium falciparum and P. vivax: a randomized controlled trial
- Artemether-lumefantrine versus chloroquine for the treatment of uncomplicated Plasmodium knowlesi malaria: an open-label randomized controlled trial (CAN KNOW)
- Global extent of chloroquine-resistant Plasmodium vivax a systematic review and meta-analysis
- Making the most of clinical data: reviewing the role of pharmacokinetic-pharmacodynamic models of anti-malarial drugs
- Treatment policy change to dihydroartemisinin-piperaquine contributes to the reduction of adverse maternal and pregnancy outcomes
- Declining transmission and immunity to malaria and emerging artemisinin resistance in Thailand: a longitudinal study
- Efficacy of artesunate-mefloquine for chloroquine-resistant Plasmodium vivax malaria in Malaysia: an open-label randomised controlled trial
- Structure- and function-based design of Plasmodium-selective proteasome inhibitors
- Targeting the cell stress response of Plasmodium falciparum to overcome artemisinin resistance
- Safety, tolerability, pharmacokinetics, and activity of the novel long-acting antimalarial DSM265: a two-part first-in-human phase 1a/1b randomised study
- Host immunity to Plasmodium falciparum and the assessment of emerging artemisinin resistance in a multinational cohort
- A dynamic stress model explains the delayed drug effect in artemisinin treatment of Plasmodium falciparum
- A mechanistic model quantifies artemisinin-induced parasite growth retardation in blood-stage Plasmodium falciparum infection
- The complex relationship of exposure to new Plasmodium infections and clinical incidence in PNG