October 26, 2022
Paolo completed a comprehensive meta-population genetic analysis of the diversity and immune selection hotspots of the leading Plasmodium vivax antigen candidate genes and sero-surveillance markers. He measured patterns of genetic diversity and selection pressure using traditional population genetics, Tajima’s D, haplotype network analysis, and structural bioinformatics. Information gathered from his study will guide researchers on the rational selection of antigen gene constructs to be included in designing a widely effective vaccine against Plasmodium vivax
Paolo Bareng, PhD Student, Institute for Mental and Physical Health and Clinical Translation (IMPACT), Deakin University and the Centre for Innovation in Infectious Diseases and Immunology Research (CIIDIR)